31 Aug, 2009 in
Questions & Answers by
admin
Hopefully, Spreedog answers this Q 
. Maybe he (or, someone else) will possess a much best answer. But, I’ll give this a shot…
I found a 1997, where cohorts of asbestos sprayers as well as silicosis patients were tracked for incidence of cancer. Total cancer, lung cancer, as well as mesothelioma were dependent/criterion variables (<-not familiar with the statistics utilized), from what I saw. I realize this research is a little dated. There is no control group, but just looks similar a report on incidence, but, still, not very much control to attribute results to isolated effects. Anyway, from what I read, standardized incidence ratios indicated that asbestos sprayers had a significantly higher incidence in the development of mesothelioma. Silicosis patients only had significantly higher incidence ratios for all sites (i.e., total cancer risk). Check out the abstract for yourself:
http://www.ncbi.nlm.nih.gov/pubmed/91312…
Interesting little bits to do with silicosis as well as asbestos-related diseases. More recent, but not quite relevant to your Q: Apparently, silicosis as well as asbestos-related diseases not only differ in their causative materials (obviously, really), but as well as in terms of complications; autoimmune disorders being ordinary in silicosis as well as tumors in asbestos-related diseases. Asbestos-related disease patients as well as show restricted overpresentation of TcR-Vbeta without clonal expansion, whereas silicosis patients reveal significant overpresentation of TcR-Vbeta 7.2. Basically, it may be concluded, here, that there are superantigenic effects associated with asbestos as well as dysregulation of autoimmunity-inducing effects of silica. I include these aforementioned bits, for the sake of interest, really, but perhaps you may glean something related to your reasoning/background to do with asking the Q. Here is the relevant abstract:
http://www.ncbi.nlm.nih.gov/pubmed/17166…
EDIT: Below, scroll down to the graph entitled, "CDC asbestosis vs silicosis deaths" associated with "Attachment 1". It's not a very cloudless graph. Pesky. But, on quick skim, it looks similar a comparison of those with either asbestosis or silicosis who expired due to malignant mesothelioma, from 1980 thru 2002. Looks similar, asbestosis on the rise as well as a bigger killer (?):
http://newbfaq.com/pdf/casualty/asbe…
